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Metabolic activation of acetylenic substituents to derivatives in the rat causing the loss of hepatic cytochrome P-450 and haem

1. A number of acetylenic-substituted steroidal and non-steroidal compounds, including 2,2-dipropargylacetamide, pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol (Danazol) and acetylene gas, when administered to rats in vivo brought about a decrease in the concentrations of hepatic microsomal cytochrome...

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Bibliografske podrobnosti
Glavni avtor: White, Ian N. H.
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1185990/
https://ncbi.nlm.nih.gov/pubmed/728091
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