Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications

OPN (osteopontin) is an integrin-binding highly phosphorylated glycoprotein, recognized as a key molecule in a multitude of biological processes such as bone mineralization, cancer metastasis, cell-mediated immune response, inflammation and cell survival. A significant regulation of OPN function is...

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Hlavní autoři: Christensen, Brian, Nielsen, Mette S., Haselmann, Kim F., Petersen, Torben E., Sørensen, Esben S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2005
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184582/
https://ncbi.nlm.nih.gov/pubmed/15869464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050341
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