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An ordered sequential mechanism for Factor IX and Factor IXa binding to platelet receptors in the assembly of the Factor X-activating complex

To define the contributions of the Ω-loop of the Gla (γ-carboxyglutamic acid) domain and the EGF2 (second epidermal growth factor) domain of FIXa (Factor IXa) in the assembly of the FX-activating complex on activated platelets and phospholipid membranes, three recombinant FIXa chimeras were prepared...

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Detalles Bibliográficos
Main Authors: Yang, Xia, Walsh, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184571/
https://ncbi.nlm.nih.gov/pubmed/15755260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050029
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