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The role of the second growth-factor domain of human factor IXa in binding to platelets and in factor-X activation.

To study the structural requirements for factor IXa binding to platelets, we have carried out equilibrium binding studies with human factor IXa after replacing the second epidermal growth factor (EGF) domain by the corresponding polypeptide region of factor X. The chimeric protein, factor IX(Xegf2),...

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Detalhes bibliográficos
Main Authors: Ahmad, S S, Rawala, R, Cheung, W F, Stafford, D W, Walsh, P N
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135912/
https://ncbi.nlm.nih.gov/pubmed/7654178
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