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The role of the second growth-factor domain of human factor IXa in binding to platelets and in factor-X activation.

To study the structural requirements for factor IXa binding to platelets, we have carried out equilibrium binding studies with human factor IXa after replacing the second epidermal growth factor (EGF) domain by the corresponding polypeptide region of factor X. The chimeric protein, factor IX(Xegf2),...

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Autors principals: Ahmad, S S, Rawala, R, Cheung, W F, Stafford, D W, Walsh, P N
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1135912/
https://ncbi.nlm.nih.gov/pubmed/7654178
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