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Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

The HTLV-1 Tax oncoprotein rapidly induces cytogenetic damage which can be measured by a significant increase in the number of micronuclei (MN) in cells. Tax is thought to have both aneuploidogenic and clastogenic effects. To examine the cellular target for Tax which might mechanistically explain th...

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Autors principals: Majone, Franca, Luisetto, Roberto, Zamboni, Daniela, Iwanaga, Yoichi, Jeang, Kuan-Teh
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184100/
https://ncbi.nlm.nih.gov/pubmed/16014171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-45
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