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Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

The HTLV-1 Tax oncoprotein rapidly induces cytogenetic damage which can be measured by a significant increase in the number of micronuclei (MN) in cells. Tax is thought to have both aneuploidogenic and clastogenic effects. To examine the cellular target for Tax which might mechanistically explain th...

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Detalhes bibliográficos
Main Authors: Majone, Franca, Luisetto, Roberto, Zamboni, Daniela, Iwanaga, Yoichi, Jeang, Kuan-Teh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184100/
https://ncbi.nlm.nih.gov/pubmed/16014171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-45
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