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The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells
TMPRSS2 is a type II transmembrane-bound serine protease that has gained interest owing to its highly localized expression in the prostate and its overexpression in neoplastic prostate epithelium. Once activated, the serine protease domain of TMPRSS2 is released from the cell surface into the extrac...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1183478/ https://ncbi.nlm.nih.gov/pubmed/15537383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041066 |
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