Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model

The envelope glycoprotein (Env) of human immunodeficiency viruses (HIVs) and simian immunodeficiency viruses (SIVs) is heavily glycosylated, and this feature has been speculated to be a reason for the insufficient immune control of these viruses by their hosts. In a macaque AIDS model, we demonstrat...

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Bibliographic Details
Main Authors: Mori, Kazuyasu, Sugimoto, Chie, Ohgimoto, Shinji, Nakayama, Emi E., Shioda, Tatsuo, Kusagawa, Shigeru, Takebe, Yutaka, Kano, Munehide, Matano, Tetsuro, Yuasa, Takae, Kitaguchi, Daisuke, Miyazawa, Masaaki, Takahashi, Yumiko, Yasunami, Michio, Kimura, Akinori, Yamamoto, Naoki, Suzuki, Yasuo, Nagai, Yoshiyuki
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182680/
https://ncbi.nlm.nih.gov/pubmed/16051831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10386-10396.2005
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