Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model

The envelope glycoprotein (Env) of human immunodeficiency viruses (HIVs) and simian immunodeficiency viruses (SIVs) is heavily glycosylated, and this feature has been speculated to be a reason for the insufficient immune control of these viruses by their hosts. In a macaque AIDS model, we demonstrat...

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Détails bibliographiques
Auteurs principaux: Mori, Kazuyasu, Sugimoto, Chie, Ohgimoto, Shinji, Nakayama, Emi E., Shioda, Tatsuo, Kusagawa, Shigeru, Takebe, Yutaka, Kano, Munehide, Matano, Tetsuro, Yuasa, Takae, Kitaguchi, Daisuke, Miyazawa, Masaaki, Takahashi, Yumiko, Yasunami, Michio, Kimura, Akinori, Yamamoto, Naoki, Suzuki, Yasuo, Nagai, Yoshiyuki
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182680/
https://ncbi.nlm.nih.gov/pubmed/16051831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10386-10396.2005
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