Influence of Glycosylation on the Efficacy of an Env-Based Vaccine against Simian Immunodeficiency Virus SIVmac239 in a Macaque AIDS Model

The envelope glycoprotein (Env) of human immunodeficiency viruses (HIVs) and simian immunodeficiency viruses (SIVs) is heavily glycosylated, and this feature has been speculated to be a reason for the insufficient immune control of these viruses by their hosts. In a macaque AIDS model, we demonstrat...

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Detalhes bibliográficos
Main Authors: Mori, Kazuyasu, Sugimoto, Chie, Ohgimoto, Shinji, Nakayama, Emi E., Shioda, Tatsuo, Kusagawa, Shigeru, Takebe, Yutaka, Kano, Munehide, Matano, Tetsuro, Yuasa, Takae, Kitaguchi, Daisuke, Miyazawa, Masaaki, Takahashi, Yumiko, Yasunami, Michio, Kimura, Akinori, Yamamoto, Naoki, Suzuki, Yasuo, Nagai, Yoshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182680/
https://ncbi.nlm.nih.gov/pubmed/16051831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10386-10396.2005
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