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Mutations of a Residue within the Polyproline-Rich Region of Env Alter the Replication Rate and Level of Cytopathic Effects in Chimeric Avian Retroviral Vectors

Previous attempts to extend the host range of the avian sarcoma/leukosis virus (ASLV)-based RCASBP vectors produced two viral vectors, RCASBP M2C (4070A) and RCASBP M2C (797-8), which replicate using the amphotropic murine leukemia virus 4070A Env protein (2). Both viruses were adapted to replicate...

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Bibliografske podrobnosti
Main Authors: Chang, Kevin W., Barsov, Eugene V., Ferris, Andrea L., Hughes, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182669/
https://ncbi.nlm.nih.gov/pubmed/16051819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10258-10267.2005
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