Human Endogenous Retroviral Long Terminal Repeat Sequences as Cell Type-Specific Promoters in Retroviral Vectors

The human genome contains more than half a million human endogenous retrovirus (HERV) long terminal repeats (LTRs) that can be regarded as mobile regulatory modules. Many of these HERV LTRs have been recruited during evolution as transcriptional control elements for cellular gene expression. We have...

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Bibliographic Details
Main Authors: Schön, Ulrike, Diem, Olivia, Leitner, Laura, Günzburg, Walter H., Mager, Dixie L., Salmons, Brian, Leib-Mösch, Christine
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786743/
https://ncbi.nlm.nih.gov/pubmed/19741000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00858-09
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