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Human Endogenous Retroviral Long Terminal Repeat Sequences as Cell Type-Specific Promoters in Retroviral Vectors

The human genome contains more than half a million human endogenous retrovirus (HERV) long terminal repeats (LTRs) that can be regarded as mobile regulatory modules. Many of these HERV LTRs have been recruited during evolution as transcriptional control elements for cellular gene expression. We have...

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Autores principales: Schön, Ulrike, Diem, Olivia, Leitner, Laura, Günzburg, Walter H., Mager, Dixie L., Salmons, Brian, Leib-Mösch, Christine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786743/
https://ncbi.nlm.nih.gov/pubmed/19741000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00858-09
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