Herpes Simplex Virus Type 1 DNA Polymerase Requires the Mammalian Chaperone Hsp90 for Proper Localization to the Nucleus

Many viruses and bacteriophage utilize chaperone systems for DNA replication and viral morphogenesis. We have previously shown that in the herpes simplex virus type 1 (HSV-1)-infected cell nucleus, foci enriched in the Hsp70/Hsp40 chaperone machinery are formed adjacent to viral replication compartm...

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Bibliographic Details
Main Authors: Burch, April D., Weller, Sandra K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182622/
https://ncbi.nlm.nih.gov/pubmed/16051866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10740-10749.2005
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