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Formaldehyde-Treated, Heat-Inactivated Virions with Increased Human Immunodeficiency Virus Type 1 Env Can Be Used To Induce High-Titer Neutralizing Antibody Responses

The lack of success of subunit human immunodeficiency virus (HIV) type 1 vaccines to date suggests that multiple components or a complex virion structure may be required. We hypothesized that the failure of current vaccine strategies to induce protective antibodies is linked to the inability of nati...

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Главные авторы: Poon, B., Hsu, J. F., Gudeman, V., Chen, I. S. Y., Grovit-Ferbas, K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182614/
https://ncbi.nlm.nih.gov/pubmed/16051814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10210-10217.2005
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