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Engineering a signal transduction mechanism for protein-based biosensors

Hybridization-induced conformational changes have been successfully used in biosensors for the transduction of DNA-binding events into readily observable optical or electronic signals. Similar signal transduction has not, however, proven of equal utility in proteinbased biosensors. The discrepancy a...

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Detalhes bibliográficos
Main Authors: Kohn, Jonathan E., Plaxco, Kevin W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182433/
https://ncbi.nlm.nih.gov/pubmed/16046542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503055102
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