Nuclear distribution and chromatin association of DNA polymerase α-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast

BACKGROUND: Cdc23/Mcm10 is required for the initiation and elongation steps of DNA replication but its biochemical function is unclear. Here, we probe its function using a novel approach in fission yeast, involving Cdc23 cleavage by the TEV protease. RESULTS: Insertion of a TEV protease cleavage sit...

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Bibliografiska uppgifter
Huvudupphovsmän: Yang, Xiaowen, Gregan, Juraj, Lindner, Karola, Young, Hedi, Kearsey, Stephen E
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2005
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182370/
https://ncbi.nlm.nih.gov/pubmed/15941470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-6-13
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