Efficient assembly of de novo human artificial chromosomes from large genomic loci

BACKGROUND: Human Artificial Chromosomes (HACs) are potentially useful vectors for gene transfer studies and for functional annotation of the genome because of their suitability for cloning, manipulating and transferring large segments of the genome. However, development of HACs for the transfer of...

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Main Authors: Basu, Joydeep, Compitello, George, Stromberg, Gregory, Willard, Huntington F, Van Bokkelen, Gil
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182356/
https://ncbi.nlm.nih.gov/pubmed/15998466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-5-21
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