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Importance of eIF2α Phosphorylation and Stress Granule Assembly in Alphavirus Translation Regulation

Alphavirus infection results in the shutoff of host protein synthesis in favor of viral translation. Here, we show that during Semliki Forest virus (SFV) infection, the translation inhibition is largely due to the activation of the cellular stress response via phosphorylation of eukaryotic translati...

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Hlavní autoři: McInerney, Gerald M., Kedersha, Nancy L., Kaufman, Randal J., Anderson, Paul, Liljeström, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182313/
https://ncbi.nlm.nih.gov/pubmed/15930128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-02-0124
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