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Importance of eIF2α Phosphorylation and Stress Granule Assembly in Alphavirus Translation Regulation

Alphavirus infection results in the shutoff of host protein synthesis in favor of viral translation. Here, we show that during Semliki Forest virus (SFV) infection, the translation inhibition is largely due to the activation of the cellular stress response via phosphorylation of eukaryotic translati...

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Detalhes bibliográficos
Main Authors: McInerney, Gerald M., Kedersha, Nancy L., Kaufman, Randal J., Anderson, Paul, Liljeström, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182313/
https://ncbi.nlm.nih.gov/pubmed/15930128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-02-0124
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