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The Complex Interplay between the Neck and Hinge Domains in Kinesin-1 Dimerization and Motor Activity
Kinesin-1 dimerizes via the coiled-coil neck domain. In contrast to animal kinesins, neck dimerization of the fungal kinesin-1 NcKin requires additional residues from the hinge. Using chimeric constructs containing or lacking fungal-specific elements, the proximal part of the hinge was shown to stab...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The American Society for Cell Biology
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1182295/ https://ncbi.nlm.nih.gov/pubmed/15901834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-11-0957 |
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