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The Complex Interplay between the Neck and Hinge Domains in Kinesin-1 Dimerization and Motor Activity

Kinesin-1 dimerizes via the coiled-coil neck domain. In contrast to animal kinesins, neck dimerization of the fungal kinesin-1 NcKin requires additional residues from the hinge. Using chimeric constructs containing or lacking fungal-specific elements, the proximal part of the hinge was shown to stab...

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Main Authors: Bathe, Friederike, Hahlen, Katrin, Dombi, Renate, Driller, Lucia, Schliwa, Manfred, Woehlke, Guenther
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182295/
https://ncbi.nlm.nih.gov/pubmed/15901834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-11-0957
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