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Increasing the Power and Efficiency of Disease-Marker Case-Control Association Studies through Use of Allele-Sharing Information

Case-control disease-marker association studies are often used in the search for variants that predispose to complex diseases. One approach to increasing the power of these studies is to enrich the case sample for individuals likely to be affected because of genetic factors. In this article, we comp...

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Detalhes bibliográficos
Main Authors: Fingerlin, Tasha E., Boehnke, Michael, Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182257/
https://ncbi.nlm.nih.gov/pubmed/14752704
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