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Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences

Techniques of comparative genomics are being used to identify candidate functional DNA sequences, and objective evaluations are needed to assess their effectiveness. Different analytical methods score distinctive features of whole-genome alignments among human, mouse, and rat to predict functional r...

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Main Authors: King, David C., Taylor, James, Elnitski, Laura, Chiaromonte, Francesca, Miller, Webb, Hardison, Ross C.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182217/
https://ncbi.nlm.nih.gov/pubmed/16024817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3642605
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