Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

We generalize the computation of the Regulatory Potential (RP) score from two-way alignments of human and mouse to three-way alignments of human, mouse, and rat. This requires overcoming technical challenges that arise because the complexity of the models underlying the score increases exponentially...

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Detalhes bibliográficos
Main Authors: Kolbe, Diana, Taylor, James, Elnitski, Laura, Eswara, Pallavi, Li, Jia, Miller, Webb, Hardison, Ross, Chiaromonte, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383316/
https://ncbi.nlm.nih.gov/pubmed/15060013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1976004
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