Regulatory Potential Scores From Genome-Wide Three-Way Alignments of Human, Mouse, and Rat

We generalize the computation of the Regulatory Potential (RP) score from two-way alignments of human and mouse to three-way alignments of human, mouse, and rat. This requires overcoming technical challenges that arise because the complexity of the models underlying the score increases exponentially...

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Main Authors: Kolbe, Diana, Taylor, James, Elnitski, Laura, Eswara, Pallavi, Li, Jia, Miller, Webb, Hardison, Ross, Chiaromonte, Francesca
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2004
Teme:
Methods
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC383316/
https://ncbi.nlm.nih.gov/pubmed/15060013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1976004
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