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Guidelines for Genotyping in Genomewide Linkage Studies: Single-Nucleotide–Polymorphism Maps Versus Microsatellite Maps

Genomewide linkage scans have traditionally employed panels of microsatellite markers spaced at intervals of ∼10 cM across the genome. However, there is a growing realization that a map of closely spaced single-nucleotide polymorphisms (SNPs) may offer equal or superior power to detect linkage, comp...

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Detalhes bibliográficos
Main Authors: Evans, David M., Cardon, Lon R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182056/
https://ncbi.nlm.nih.gov/pubmed/15311375
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