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Disentangling Linkage Disequilibrium and Linkage From Dense Single-Nucleotide Polymorphism Trio Data
Parent-offspring trios are widely collected for disease gene-mapping studies and are being extensively genotyped as part of the International HapMap Project. With dense maps of markers on trios, the effects of LD and linkage can be separated, allowing estimation of recombination rates in a model-fre...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Copyright © 2005 by the Genetics Society of America
2005
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456135/ https://ncbi.nlm.nih.gov/pubmed/16118185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.047431 |
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