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Theoretical and Empirical Power of Regression and Maximum-Likelihood Methods to Map Quantitative Trait Loci in General Pedigrees

Both theoretical calculations and simulation studies have been used to compare and contrast the statistical power of methods for mapping quantitative trait loci (QTLs) in simple and complex pedigrees. A widely used approach in such studies is to derive or simulate the expected mean test statistic un...

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Détails bibliographiques
Auteurs principaux: Yu, Xijiang, Knott, Sara A., Visscher, Peter M.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182003/
https://ncbi.nlm.nih.gov/pubmed/15152343
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