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Theoretical and Empirical Power of Regression and Maximum-Likelihood Methods to Map Quantitative Trait Loci in General Pedigrees

Both theoretical calculations and simulation studies have been used to compare and contrast the statistical power of methods for mapping quantitative trait loci (QTLs) in simple and complex pedigrees. A widely used approach in such studies is to derive or simulate the expected mean test statistic un...

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Detalles Bibliográficos
Main Authors: Yu, Xijiang, Knott, Sara A., Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182003/
https://ncbi.nlm.nih.gov/pubmed/15152343
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