MSH2 c.1452–1455delAATG Is a Founder Mutation and an Important Cause of Hereditary Nonpolyposis Colorectal Cancer in the Southern Chinese Population

Hereditary nonpolyposis colorectal cancer (HNPCC) accounts for ∼2% of all colorectal cancer (CRC) cases and is the most common hereditary CRC syndrome. We have previously reported a high incidence of microsatellite instability (MSI) and germline mismatch repair (MMR) gene mutations in young Hong Kon...

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Detalhes bibliográficos
Main Authors: Chan, Tsun Leung, Wai Chan, Yee, Ho, Judy W. C., Chan, Celine, Chan, Annie S. Y., Chan, Emily, Lam, Polly W. Y., Wah Tse, Chun, Cheong Lee, Kam, Wai Lau, Chi, Gwi, Elaine, Yi Leung, Suet, Yuen, Siu Tsan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181966/
https://ncbi.nlm.nih.gov/pubmed/15042510
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