A High-Density Admixture Map for Disease Gene Discovery in African Americans

Admixture mapping (also known as “mapping by admixture linkage disequilibrium,” or MALD) provides a way of localizing genes that cause disease, in admixed ethnic groups such as African Americans, with ∼100 times fewer markers than are required for whole-genome haplotype scans. However, it has not be...

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Main Authors: Smith, Michael W. , Patterson, Nick , Lautenberger, James A. , Truelove, Ann L. , McDonald, Gavin J. , Waliszewska, Alicja , Kessing, Bailey D. , Malasky, Michael J. , Scafe, Charles , Le, Ernest , De Jager, Philip L. , Mignault, Andre A. , Yi, Zeng , de Thé, Guy , Essex, Myron , Sankalé, Jean-Louis , Moore, Jason H. , Poku, Kwabena , Phair, John P. , Goedert, James J. , Vlahov, David , Williams, Scott M. , Tishkoff, Sarah A. , Winkler, Cheryl A. , De La Vega, Francisco M. , Woodage, Trevor , Sninsky, John J. , Hafler, David A. , Altshuler, David , Gilbert, Dennis A. , O’Brien, Stephen J. , Reich, David 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2004
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181963/
https://ncbi.nlm.nih.gov/pubmed/15088270
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