Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men

A whole-genome admixture scan in 1,597 African Americans identified a 3.8 Mb interval on chromosome 8q24 as significantly associated with susceptibility to prostate cancer [logarithm of odds (LOD) = 7.1]. The increased risk because of inheriting African ancestry is greater in men diagnosed before 72...

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Bibliografiska uppgifter
Huvudupphovsmän: Freedman, Matthew L., Haiman, Christopher A., Patterson, Nick, McDonald, Gavin J., Tandon, Arti, Waliszewska, Alicja, Penney, Kathryn, Steen, Robert G., Ardlie, Kristin, John, Esther M., Oakley-Girvan, Ingrid, Whittemore, Alice S., Cooney, Kathleen A., Ingles, Sue A., Altshuler, David, Henderson, Brian E., Reich, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599913/
https://ncbi.nlm.nih.gov/pubmed/16945910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605832103
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