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High Proportion of Mutant Osteoblasts Is Compatible with Normal Skeletal Function in Mosaic Carriers of Osteogenesis Imperfecta

Individuals with mosaicism for the autosomal dominant bone dysplasia osteogenesis imperfecta (OI) are generally identified by having more than one affected child. The mosaic carriers have both normal and mutant cell populations in somatic and germline tissues but are unaffected or minimally affected...

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Bibliografski detalji
Glavni autori: Cabral, Wayne A., Marini, Joan C.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181952/
https://ncbi.nlm.nih.gov/pubmed/15024692
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