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Population-Genetic Basis of Haplotype Blocks in the 5q31 Region

We investigated patterns of nucleotide variation in the 5q31 region identified by Daly et al. as containing haplotype blocks, to determine whether the blocklike pattern requires the assumption of hotspots in recombination. Using extensive simulations that generate data matched to the Daly et al. dat...

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Main Authors: Anderson, Eric C., Slatkin, Montgomery
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society of Human Genetics 2004
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181911/
https://ncbi.nlm.nih.gov/pubmed/14681827
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