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Absence of genetic linkage of chromosome 5q31 with asthma and atopy in the general population

BACKGROUND: Clinical asthma is associated with increased serum total immunoglobulin E (IgE), atopy (skin prick test positivity to common aeroallergens), and bronchial hyperreactivity (BHR) to non-specific stimuli (positive methacholine challenge test). A region on chromosome 5q31-33 has been linked...

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Main Authors: Kamitani, A., Wong, Z. Y., Dickson, P., van Herwerden, L., Raven, J., Forbes, A. B., Abramson, M. J., Walters, E. H., Harrap, S. B.
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1758647/
https://ncbi.nlm.nih.gov/pubmed/9371215
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