Mapping Multiple Sclerosis Susceptibility to the HLA-DR Locus in African Americans

An underlying complex genetic susceptibility exists in multiple sclerosis (MS), and an association with the HLA-DRB1*1501-DQB1*0602 haplotype has been repeatedly demonstrated in high-risk (northern European) populations. It is unknown whether the effect is explained by the HLA-DRB1 or the HLA-DQB1 g...

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Autors principals: Oksenberg, Jorge R., Barcellos, Lisa F., Cree, Bruce A. C., Baranzini, Sergio E., Bugawan, Teodorica L., Khan, Omar, Lincoln, Robin R., Swerdlin, Amy, Mignot, Emmanuel, Lin, Ling, Goodin, Douglas, Erlich, Henry A., Schmidt, Silke, Thomson, Glenys, Reich, David E., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181903/
https://ncbi.nlm.nih.gov/pubmed/14669136
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