Mapping Multiple Sclerosis Susceptibility to the HLA-DR Locus in African Americans

An underlying complex genetic susceptibility exists in multiple sclerosis (MS), and an association with the HLA-DRB1*1501-DQB1*0602 haplotype has been repeatedly demonstrated in high-risk (northern European) populations. It is unknown whether the effect is explained by the HLA-DRB1 or the HLA-DQB1 g...

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Auteurs principaux: Oksenberg, Jorge R., Barcellos, Lisa F., Cree, Bruce A. C., Baranzini, Sergio E., Bugawan, Teodorica L., Khan, Omar, Lincoln, Robin R., Swerdlin, Amy, Mignot, Emmanuel, Lin, Ling, Goodin, Douglas, Erlich, Henry A., Schmidt, Silke, Thomson, Glenys, Reich, David E., Pericak-Vance, Margaret A., Haines, Jonathan L., Hauser, Stephen L.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181903/
https://ncbi.nlm.nih.gov/pubmed/14669136
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