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Deletion of the Herpes Simplex Virus VP22-Encoding Gene (UL49) Alters the Expression, Localization, and Virion Incorporation of ICP0

The role of the herpes simplex virus tegument protein VP22 is not yet known. Here we describe the characterization of a virus in which the entire VP22 open reading frame has been deleted. We show that VP22 is not essential for virus growth but that virus lacking VP22 (Δ22) displays a cell-specific r...

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Detalhes bibliográficos
Main Authors: Elliott, Gillian, Hafezi, Wali, Whiteley, Alison, Bernard, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181569/
https://ncbi.nlm.nih.gov/pubmed/16014935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9735-9745.2005
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