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Sodium leak pathway and substrate binding order in the Na+-glucose cotransporter.

The Na+-glucose cotransporter (SGLT1) expressed in Xenopus laevis oocytes was shown to generate a phlorizin-sensitive sodium leak in the absence of sugars. Using the current model for SGLT1, where the sodium leak was presumed to occur after two sodium ions are bound to the free carrier before glucos...

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Autors principals: Chen, X Z, Coady, M J, Jalal, F, Wallendorff, B, Lapointe, J Y
Format: Artigo
Idioma:Inglês
Publicat: 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181151/
https://ncbi.nlm.nih.gov/pubmed/9370443
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