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Characterization of complex apurinic/apyrimidinic-site clustering associated with an authentic site-specific radiation-induced DNA double-strand break

Radiation lethality is largely attributed to radiation-induced DNA double-strand breaks (DSBs). A range of structural complexity is predicted for radiation-induced DSBs. However, this lesion has never been analyzed in isolation at the molecular level. To address this problem, we have created authent...

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Detalhes bibliográficos
Main Authors: Datta, Kamal, Neumann, Ronald D., Winters, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180784/
https://ncbi.nlm.nih.gov/pubmed/16024726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503975102
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