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Cooperative binding of DNA and CBFβ to the Runt domain of the CBFα studied via MD simulations

The Runt domain (RD) is the DNA-binding region of the Runx genes. A related protein, known as core binding factor β (CBFβ) also binds to the RD to enhance RD–DNA interaction by 6- to 10-fold. Here, we report results from molecular dynamics (MD) simulations of RD alone, as a dimer in complexes with D...

詳細記述

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書誌詳細
主要な著者: Habtemariam, Bahru, Anisimov, Victor M., MacKerell, Alexander D.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180745/
https://ncbi.nlm.nih.gov/pubmed/16049027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki724
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