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Cooperative binding of DNA and CBFβ to the Runt domain of the CBFα studied via MD simulations
The Runt domain (RD) is the DNA-binding region of the Runx genes. A related protein, known as core binding factor β (CBFβ) also binds to the RD to enhance RD–DNA interaction by 6- to 10-fold. Here, we report results from molecular dynamics (MD) simulations of RD alone, as a dimer in complexes with D...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1180745/ https://ncbi.nlm.nih.gov/pubmed/16049027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki724 |
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