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Assessing the Performance of the Haplotype Block Model of Linkage Disequilibrium

Several recent studies have suggested that linkage disequilibrium (LD) in the human genome has a fundamentally “blocklike” structure. However, thus far there has been little formal assessment of how well the haplotype block model captures the underlying structure of LD. Here we propose quantitative...

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Bibliografske podrobnosti
Main Authors: Wall, Jeffrey D., Pritchard, Jonathan K.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Human Genetics 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180676/
https://ncbi.nlm.nih.gov/pubmed/12916017
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