Genomewide Linkage and Linkage Disequilibrium Analyses Identify COL6A1, on Chromosome 21, as the Locus for Ossification of the Posterior Longitudinal Ligament of the Spine

Ossification of the posterior longitudinal ligament (OPLL) of the spine is a subset of “bone-forming” diseases, characterized by ectopic ossification in the spinal ligaments. OPLL is a common disorder among elderly populations in eastern Asia and is the leading cause of spinal myelopathy in Japan. W...

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Main Authors: Tanaka, Toshihiro, Ikari, Katsunori, Furushima, Kozo, Okada, Akihiro, Tanaka, Hiroshi, Furukawa, Ken-Ichi, Yoshida, Kenichi, Ikeda, Toshiyuki, Ikegawa, Shiro, Hunt, Steven C., Takeda, Jun, Toh, Satoshi, Harata, Seiko, Nakajima, Toshiaki, Inoue, Ituro
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180604/
https://ncbi.nlm.nih.gov/pubmed/12958705
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