Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans

The signaling molecule cyclic AMP (cAMP) is a ubiquitous second messenger that enables cells to detect and respond to extracellular signals. cAMP is generated by the enzyme adenylyl cyclase, which is activated or inhibited by the Gα subunits of heterotrimeric G proteins in response to ligand-activat...

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Main Authors: Alspaugh, J. Andrew, Pukkila-Worley, Read, Harashima, Toshiaki, Cavallo, Lora M., Funnell, Deanna, Cox, Gary M., Perfect, John R., Kronstad, James W., Heitman, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC118042/
https://ncbi.nlm.nih.gov/pubmed/12455973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.1.1.75-84.2002
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