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The Pedigree Rate of Sequence Divergence in the Human Mitochondrial Genome: There Is a Difference Between Phylogenetic and Pedigree Rates

We have extended our previous analysis of the pedigree rate of control-region divergence in the human mitochondrial genome. One new germline mutation in the mitochondrial DNA (mtDNA) control region was detected among 185 transmission events (generations) from five Leber hereditary optic neuropathy (...

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Библиографические подробности
Главные авторы: Howell, Neil, Smejkal, Christy Bogolin, Mackey, D. A., Chinnery, P. F., Turnbull, D. M., Herrnstadt, Corinna
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society of Human Genetics 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180241/
https://ncbi.nlm.nih.gov/pubmed/12571803
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