Phylogenetic Analysis of the Mitochondrial Genomes from Leber Hereditary Optic Neuropathy Pedigrees

The nucleotide sequences of the mitochondrial genomes from patients with Leber hereditary optic neuropathy (LHON) were used for phylogenetic analysis to study the origin and population history of pathogenic mitochondrial mutations. Sequences of both the coding region (8300 bp) and the more rapidly e...

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Bibliographic Details
Main Authors: Howell, N., Kubacka, I., Halvorson, S., Howell, B., McCullough, D. A., Mackey, D.
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1206556/
https://ncbi.nlm.nih.gov/pubmed/7635294
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