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Formation of N′-formylkynurenine in proteins from lens and other sources by exposure to sunlight

The photo-oxidative effect of sunlight on the tryptophan residues of proteins and on free tryptophan is described. Evidence is presented that the indole ring is split to yield N′-formylkynurenine. The possible relation of this photo-oxidative change to changes in the lens proteins of brown cataracts...

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Autor principal: Pirie, Antoinette
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1178040/
https://ncbi.nlm.nih.gov/pubmed/5168391
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