Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

BACKGROUND: In the present study, by comparing the responses in wild-type mice (WT) and mice lacking (KO) the inducible (or type 2) nitric oxide synthase (iNOS), we investigated the role played by iNOS in the development of on the lung injury caused by bleomycin administration. When compared to bleo...

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Hlavní autoři: Genovese, Tiziana, Cuzzocrea, Salvatore, Di Paola, Rosanna, Failla, Marco, Mazzon, Emanuela, Sortino, Maria Angela, Frasca, Giuseppina, Gili, Elisa, Crimi, Nunzio, Caputi, Achille P, Vancheri, Carlo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177992/
https://ncbi.nlm.nih.gov/pubmed/15955252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-58
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