Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

BACKGROUND: In the present study, by comparing the responses in wild-type mice (WT) and mice lacking (KO) the inducible (or type 2) nitric oxide synthase (iNOS), we investigated the role played by iNOS in the development of on the lung injury caused by bleomycin administration. When compared to bleo...

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Bibliografiske detaljer
Main Authors: Genovese, Tiziana, Cuzzocrea, Salvatore, Di Paola, Rosanna, Failla, Marco, Mazzon, Emanuela, Sortino, Maria Angela, Frasca, Giuseppina, Gili, Elisa, Crimi, Nunzio, Caputi, Achille P, Vancheri, Carlo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1177992/
https://ncbi.nlm.nih.gov/pubmed/15955252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-58
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