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Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
Parkin, an E3 ubiquitin ligase, has been found to be responsible for autosomal recessive juvenile parkinsonism characterized primarily by selective loss of dopaminergic neurons with subsequent defects in movements. However, the molecular mechanisms underlying this neuron loss remain elusive. Here, w...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1177361/ https://ncbi.nlm.nih.gov/pubmed/16002472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500346102 |
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