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Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

BACKGROUND: During the translation of mRNA into polypeptide, elongation factor G (EF-G) catalyzes the translocation of peptidyl-tRNA from the A site to the P site of the ribosome. According to the 'classical' model, EF-G in the GTP-bound form promotes translocation, while hydrolysis of the...

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Detalhes bibliográficos
Main Authors: Zavialov, Andrey V, Hauryliuk, Vasili V, Ehrenberg, Måns
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175996/
https://ncbi.nlm.nih.gov/pubmed/15985150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol24
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