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Creatine synthesis and transport during rat embryogenesis: Spatiotemporal expression of AGAT, GAMT and CT1

BACKGROUND: Creatine (Cr) is synthesized by a two-step mechanism involving arginine:glycine amidinotransferase (AGAT) and guanidinoacetate methyltransferase (GAMT), and is taken up by cells through a specific Cr transporter, CT1. Recently, genetic defects of this pathway have been described, that le...

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Main Authors: Braissant, Olivier, Henry, Hugues, Villard, Anne-Marie, Speer, Oliver, Wallimann, Theo, Bachmann, Claude
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1175845/
https://ncbi.nlm.nih.gov/pubmed/15918910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-5-9
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